Publicações relacionadas à zika

In:

Nature Medicine

Author:

Rachel Becker

When Patricia Pestana Garcez returned home to Brazil to start her new position as an assistant professor at the Federal University of Rio de Janeiro in June, she knew that she would study the neurobiology of brain malformations. But she hadn’t yet decided whether to continue her research into microcephaly, a birth defect characterized by an unusually small head and caused by genetic mutation or maternal infection.

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In:

Wiley Online Library

Authors:

A. S. Oliveira Melo, G. Malinger, R. Ximenes, P. O. Szejnfeld, S. Alves Sampaio and A. M. Bispo de Filippis

Zika virus intrauterine infection causes fetal brain abnormality and microcephaly: tip of the iceberg?

An unexpected upsurge in diagnosis of fetal and pediatric microcephaly has been reported in the Brazilian press recently. Cases have been diagnosed in nine Brazilian states so far. By 28 November 2015, 646 cases had been reported in Pernambuco state alone. Although reports have circulated regarding the declaration of a state of national health emergency, there is no information on the imaging and clinical findings of affected cases. Authorities are considering different theories behind the ‘microcephaly outbreak’, including a possible association with the emergence of Zika virus disease within the region, the first case of which was detected in May 20151.

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In:

Blood Transfusion

Authors:

Giuseppe Marano, Simonetta Pupella, Stefania Vaglio, Giancarlo M. Liumbruno, Giuliano Grazzini

Abstract

In the last few years, the transfusion medicine community has been paying special attention to emerging vector-borne diseases transmitted by arboviruses. Zika virus is the latest of these pathogens and is responsible for major outbreaks in Africa, Asia and, more recently, in previously infection-naïve territories of the Pacific area. Many issues regarding this emerging pathogen remain unclear and require further investigation. National health authorities have adopted different prevention strategies. The aim of this review article is to discuss the currently available, though limited, information and the potential impact of this virus on transfusion medicine.

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In:

Revista da Sociedade Brasileira de Medicina Tropical

Authors:

Carlos Brisola Marcondes and Maria de Fátima Freire de Melo Ximenes

Abstract

Zika virus, already widely distributed in Africa and Asia, was recently reported in two Northeastern Brazilian: State of Bahia and State of Rio Grande do Norte, and one Southeastern: State of São Paulo. This finding adds a potentially noxious virus to a list of several other viruses that are widely transmitted by Aedes (Stegomyia) aegypti and Aedes (Stegomyia) albopictus in Brazil. The pathology and epidemiology, including the distribution and vectors associated with Zika virus, are reviewed. This review is focused on viruses transmitted by Aedes (Stegomyia) mosquitoes, including dengue, Chikungunya, Zika, Mayaro, and yellow fever virus, to emphasize the risks of occurrence for these arboviruses in Brazil and neighboring countries. Other species of
Aedes (Stegomyia) are discussed, emphasizing their involvement in arbovirus transmission and the possibility of adaptation to environments modified by human activities and introduction in Brazil.

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In:

Neglected Tropical Diseases

Authors:

Jeremy P. Ledermann, Laurent Guillaumot, Lawrence Yug, Steven C. Saweyog, Mary Tided, Paul Machieng, Moses Pretrick, Maria Marfel, Anne Griggs, Martin Bel, Mark R. Duffy, W. Thane Hancock, Tai Ho-Chen, Ann M. Powers

Abstract

An epidemic of Zika virus (ZIKV) illness that occurred in July 2007 on Yap Island in the Federated States of Micronesia prompted entomological studies to identify both the primary vector(s) involved in transmission and the ecological parameters contributing to the outbreak. Larval and pupal surveys were performed to identify the major containers serving as oviposition habitat for the likely vector(s). Adult mosquitoes were also collected by backpack aspiration, light trap, and gravid traps at select sites around the capital city. The predominant species found on the island was Aedes (Stegomyia) hensilli. No virus isolates were obtained from the adult field material collected, nor did any of the immature mosquitoes that were allowed to emerge to adulthood contain viable virus or nucleic acid. Therefore, laboratory studies of the probable vector, Ae. hensilli, were undertaken to determine the likelihood of this species serving as a vector for Zika virus and other arboviruses. Infection rates of up to 86%, 62%, and 20% and dissemination rates of 23%, 80%, and 17% for Zika, chikungunya, and dengue-2 viruses respectively, were found supporting the possibility that this species served as a vector during the Zika outbreak and that it could play a role in transmitting other medically important arboviruses.

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