Publicações relacionadas à zika
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In:
The Lancet
Authors:
Cesar Gomes Victora, Lavinia Schuler-Faccini, Alicia Matijasevich, Erlane Ribeiro, André Pessoa, Fernando Celso Barros
Brazil is facing its fi rst outbreak of Zika virus, particularly in the northeast region. Most cases of Zika virus infection are self-limited and without sequelae, but there have been clusters of cases of microcephaly in some areas of known Zika virus transmission. Although strongly suspected, the causal relation between in-utero exposure to Zika and microcephaly is yet to be established. The increased number of microcephaly cases in Brazil has led to a high level of concern among pregnant women throughout the country. On Feb 1, 2016, WHO’s International Health Regulations Emergency Committee advised that the clusters of microcephaly and other neurological disorders and their possible association with Zika virus constitutes a Public Health Emergency of International Concern.1
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In:
Microbiological Reviews
The expression "vertical transmission" refers to the direction of transmission when family trees are drawn on paper. They are represented as lines beginning from a trunk (the ancestors) at the top of the page, the descendants occupying the proliferating branches further down the page. It was because such diagrams looked like the branching digits of a bird that the word pedigree (pied de grue = foot of the crane) came into our language. Relationships that are in this sense vertical have been the classical concem of the geneticist, and the hereditary elements are transmitted down the page, and down from generation to generation. The vertical axis is time, and a given hereditary unit (gene) can in this way be charted over the course of many generations. This is in contrast to the transmission of materials between individuals who are living at the same time, this being represented as a more or less horizontal line on the diagram. Horizontal transmission can take place between related or between unrelated individuals.
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In:
Centers for Disease Control and Prevention
Authors:
Susan L. Hills, MBBS ; Kate Russell, MD ; Morgan Hennessey, DVM ; Charnetta Williams, MD; Alexandra M. Oster, MD ; Marc Fischer, MD ; Paul Mead, MD
Summary
What is already known about this topic?
Zika virus is spread primarily by Aedes species mosquitoes, though recent reports have described two instances of sexual transmission of Zika virus, and replicative virus has been isolated from semen of one man with hematospermia. CDC released interim guidance for prevention of sexual transmission of Zika virus on February 5, 2016.
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In:
The Lancet
Authors:
Camila V Ventura, Mauricio Maia, Vasco Bravo-Filho, Adriana L Góis, Rubens Belfort Jr
Zika virus (ZIKV), a mosquito-borne Flavivirus, was fi rst reported in human beings in 1952.1 Before April, 2015, no case had been reported in Brazil. However, between April and November, 2015, 18 of the 27 Brazilian states reported ZIKV autochthonous cases.2
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In:
Archives of Virology
Authors:
J. Tognarelli, S. Ulloa, E. Villagra, J. Lagos, C. Aguayo, R. Fasce, B. Parra, J. Mora, N. Becerra, N. Lagos, L. Vera, B. Olivares, M. Vilches, J. Fernández
Abstract
Zika virus (ZIKV) is an emerging mosquitoborne flavivirus circulating in Asia and Africa. In 2013, a large outbreak was reported on the archipelago of French Polynesia. In this study, we report the detection and molecular characterization of Zika virus for the first time in Chile from an outbreak among the inhabitants of Easter Island. A total of 89 samples from patients suspected of having ZIKV infection were collected between the period from January to May, 2014. Molecular diagnosis of the virus was performed by RT-PCR followed by the sequencing of the region containing the NS5 gene. A comparison of the viral nucleic acid sequence with those of other strains of ZIKA virus was performed using the MEGA software. Fifty-one samples were found positive for ZIKV by RT-PCR analysis. Further analysis of the NS5 gene revealed that the ZIKV strains identified in Easter, Island were most closely related to those found in French Polynesia (99.8 to 99.9 % nt and 100 % aa sequence identity). These results strongly suggest that the transmission pathway leading to the introduction of Zika virus on Easter Island has its origin in French Polynesia.
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