In:

Emerging Infectious Diseases

Authors:

Myrielle Dupont-Rouzeyrol, Olivia O’Connor, Elodie Calvez, Maguy Daures, Michèle John, Jean-Paul Grangeon, Ann-Claire Gourinat

Dengue is the most prevalent arthropod-borne viral disease in tropical and subtropical countries. Every year, dengue virus (DENV) infections cause more than 50 million cases, 500,000 hospitalizations, and 12,500 deaths worldwide (1). DENV belongs to the genus Flavivirus and is transmitted by Aedes spp. mosquitoes. There are 4 distinct serotypes (DENV-1 to DENV-4), and infection with 1 serotype does not provide long-term, cross-protective immunity against the other 3 serotypes.

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