In:

American Journal of Public Health

Authors:

Enny S. Paixão, MSc, Florisneide Barreto, PhD, Maria da Glória Teixeira, PhD, Maria da Conceição N. Costa, PhD, and Laura C. Rodrigues, PhD

Objectives. To describe salient epidemiological characteristics of Zika virus outbreaks across the world and to examine the clinical presentations, complications, and atypical manifestations related to their occurrence in recent history.

Methods. We conducted a systematic review of the literature by searching through MEDLINE, Embase, and Global Health Library, as well as the epidemiological bulletins and alerts from the World Health Organization, the Pan American Health Organization, and the European Centre for Disease Prevention and Control over the period 1954 to 2016.

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