In:

American Journal of Obstetrics & Gynecology

Authors:

Kjersti Aagaard, Melissa Suter, Maxim Seferovic, Min Hu, Maike Kahr, Catherine Eppes, Martha Rac, Michael Belfort

OBJECTIVE: Zika virus (ZIKV) is an emerging mosquito-borne flavivirus. A causal link explaining the delay between maternal symptoms and fetal infection is missing, and why prior African outbreaks were not associated with fetal malformations is unknown. In this study, we sought to answer these questions using state-of-the-science approaches with a single passage contemporary
ZIKV strain and infection of high purity trophoblasts from uninfected donors.

Download full publication: